Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis.

Briukhovetska, Daria; Suarez-Gosalvez, Javier; Voigt, Cornelia; Markota, Anamarija; Giannou, Anastasios D; Schübel, Maryam; Jobst, Jakob; Zhang, Tao; Dörr, Janina; Märkl, Florian; Majed, Lina; Müller, Philipp Jie; May, Peter; Gottschlich, Adrian; Tokarew, Nicholas; Lücke, Jöran; Oner, Arman; Schwerdtfeger, Melanie; Andreu-Sanz, David; Grünmeier, Ruth; Seifert, Matthias; Michaelides, Stefanos; Hristov, Michael; König, Lars M; Cadilha, Bruno Loureiro; Mikhaylov, Oleg; Anders, Hans-Joachim; Rothenfusser, Simon; Flavell, Richard A; Cerezo-Wallis, Daniela; Tejedo, Cristina; Soengas, María S; Bald, Tobias; Huber, Samuel; Endres, Stefan; Kobold, Sebastian.

Immunity ; 56(1): 143-161.e11, 2023 01 10.

Artigo em Inglês | MEDLINE | ID: mdl-36630913

2.

Distinct and dynamic activation profiles of circulating dendritic cells and monocytes in mild COVID-19 and after yellow fever vaccination.

Winheim, Elena; Eser, Tabea; Deák, Flora; Ahmed, Mohamed I M; Baranov, Olga; Rinke, Linus; Eisenächer, Katharina; Santos-Peral, Antonio; Karimzadeh, Hadi; Pritsch, Michael; Scherer, Clemens; Muenchhoff, Maximilian; Hellmuth, Johannes C; von Bergwelt-Baildon, Michael; Olbrich, Laura; Hoelscher, Michael; Wieser, Andreas; Kroidl, Inge; Rothenfusser, Simon; Geldmacher, Christof; Krug, Anne B.

Eur J Immunol ; 53(3): e2250090, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-36404054

3.

Impaired function and delayed regeneration of dendritic cells in COVID-19.

Winheim, Elena; Rinke, Linus; Lutz, Konstantin; Reischer, Anna; Leutbecher, Alexandra; Wolfram, Lina; Rausch, Lisa; Kranich, Jan; Wratil, Paul R; Huber, Johanna E; Baumjohann, Dirk; Rothenfusser, Simon; Schubert, Benjamin; Hilgendorff, Anne; Hellmuth, Johannes C; Scherer, Clemens; Muenchhoff, Maximilian; von Bergwelt-Baildon, Michael; Stark, Konstantin; Straub, Tobias; Brocker, Thomas; Keppler, Oliver T; Subklewe, Marion; Krug, Anne B.

PLoS Pathog ; 17(10): e1009742, 2021 10.

Artigo em Inglês | MEDLINE | ID: mdl-34614036

4.

Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production.

Poeck, Hendrik; Bscheider, Michael; Gross, Olaf; Finger, Katrin; Roth, Susanne; Rebsamen, Manuele; Hannesschläger, Nicole; Schlee, Martin; Rothenfusser, Simon; Barchet, Winfried; Kato, Hiroki; Akira, Shizuo; Inoue, Satoshi; Endres, Stefan; Peschel, Christian; Hartmann, Gunther; Hornung, Veit; Ruland, Jürgen.

Nat Immunol ; 11(1): 63-9, 2010 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-19915568

5.

Metabolic implication of tigecycline as an efficacious second-line treatment for sorafenib-resistant hepatocellular carcinoma.

Meßner, Martina; Schmitt, Sabine; Ardelt, Maximilian A; Fröhlich, Thomas; Müller, Martin; Pein, Helmut; Huber-Cantonati, Petra; Ortler, Carina; Koenig, Lars M; Zobel, Lena; Koeberle, Andreas; Arnold, Georg J; Rothenfußer, Simon; Kiemer, Alexandra K; Gerbes, Alexander L; Zischka, Hans; Vollmar, Angelika M; Pachmayr, Johanna.

FASEB J ; 34(9): 11860-11882, 2020 09.

Artigo em Inglês | MEDLINE | ID: mdl-32652772

6.

To Protect Fatty Livers from Ischemia Reperfusion Injury: Role of Ischemic Postconditioning.

Schewe, Julia; Makeschin, Marie-Christine; Khandoga, Andrej; Zhang, Jiang; Mayr, Doris; Rothenfußer, Simon; Schnurr, Max; Gerbes, Alexander L; Steib, Christian J.

Dig Dis Sci ; 66(4): 1349-1359, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-32451758

7.

Inhibition of Cyclin-Dependent Kinase 5: A Strategy to Improve Sorafenib Response in Hepatocellular Carcinoma Therapy.

Ardelt, Maximilian A; Fröhlich, Thomas; Martini, Emanuele; Müller, Martin; Kanitz, Veronika; Atzberger, Carina; Cantonati, Petra; Meßner, Martina; Posselt, Laura; Lehr, Thorsten; Wojtyniak, Jan-Georg; Ulrich, Melanie; Arnold, Georg J; König, Lars; Parazzoli, Dario; Zahler, Stefan; Rothenfußer, Simon; Mayr, Doris; Gerbes, Alexander; Scita, Giorgio; Vollmar, Angelika M; Pachmayr, Johanna.

Hepatology ; 69(1): 376-393, 2019 01.

Artigo em Inglês | MEDLINE | ID: mdl-30033593

8.

Cancer cells induce interleukin-22 production from memory CD4⁺ T cells via interleukin-1 to promote tumor growth.

Voigt, Cornelia; May, Peter; Gottschlich, Adrian; Markota, Anamarija; Wenk, Daniel; Gerlach, Inga; Voigt, Sebastian; Stathopoulos, Georgios T; Arendt, Kristina A M; Heise, Constanze; Rataj, Felicitas; Janssen, Klaus-Peter; Königshoff, Melanie; Winter, Hauke; Himsl, Isabelle; Thasler, Wolfgang E; Schnurr, Max; Rothenfußer, Simon; Endres, Stefan; Kobold, Sebastian.

Proc Natl Acad Sci U S A ; 114(49): 12994-12999, 2017 12 05.

Artigo em Inglês | MEDLINE | ID: mdl-29150554

9.

Polymorphisms in melanoma differentiation-associated gene 5 link protein function to clearance of hepatitis C virus.

Hoffmann, Franziska S; Schmidt, Andreas; Dittmann Chevillotte, Meike; Wisskirchen, Christian; Hellmuth, Johannes; Willms, Simone; Gilmore, Rachel H; Glas, Jürgen; Folwaczny, Matthias; Müller, Tobias; Berg, Thomas; Spengler, Ulrich; Fitzmaurice, Karen; Kelleher, Dermot; Reisch, Nicole; Rice, Charles M; Endres, Stefan; Rothenfusser, Simon.

Hepatology ; 61(2): 460-70, 2015 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-25130193

10.

Cytosolic DNA triggers mitochondrial apoptosis via DNA damage signaling proteins independently of AIM2 and RNA polymerase III.

Wenzel, Michael; Wunderlich, Michael; Besch, Robert; Poeck, Hendrik; Willms, Simone; Schwantes, Astrid; Kremer, Melanie; Sutter, Gerd; Endres, Stefan; Schmidt, Andreas; Rothenfusser, Simon.

J Immunol ; 188(1): 394-403, 2012 Jan 01.

Artigo em Inglês | MEDLINE | ID: mdl-22140256

11.

Prior flavivirus immunity skews the yellow fever vaccine response to cross-reactive antibodies with potential to enhance dengue virus infection.

Santos-Peral, Antonio; Luppa, Fabian; Goresch, Sebastian; Nikolova, Elena; Zaucha, Magdalena; Lehmann, Lisa; Dahlstroem, Frank; Karimzadeh, Hadi; Thorn-Seshold, Julia; Winheim, Elena; Schuster, Ev-Marie; Dobler, Gerhard; Hoelscher, Michael; Kümmerer, Beate M; Endres, Stefan; Schober, Kilian; Krug, Anne B; Pritsch, Michael; Barba-Spaeth, Giovanna; Rothenfusser, Simon.

Nat Commun ; 15(1): 1696, 2024 Feb 24.

Artigo em Inglês | MEDLINE | ID: mdl-38402207

12.

Receptor transfer between immune cells by autoantibody-enhanced, CD32-driven trogocytosis is hijacked by HIV-1 to infect resting CD4 T cells.

Albanese, Manuel; Chen, Hong-Ru; Gapp, Madeleine; Muenchhoff, Maximilian; Yang, Hsiu-Hui; Peterhoff, David; Hoffmann, Katja; Xiao, Qianhao; Ruhle, Adrian; Ambiel, Ina; Schneider, Stephanie; Mejías-Pérez, Ernesto; Stern, Marcel; Wratil, Paul R; Hofmann, Katharina; Amann, Laura; Jocham, Linda; Fuchs, Thimo; Ulivi, Alessandro F; Besson-Girard, Simon; Weidlich, Simon; Schneider, Jochen; Spinner, Christoph D; Sutter, Kathrin; Dittmer, Ulf; Humpe, Andreas; Baumeister, Philipp; Wieser, Andreas; Rothenfusser, Simon; Bogner, Johannes; Roider, Julia; Knolle, Percy; Hengel, Hartmut; Wagner, Ralf; Laketa, Vibor; Fackler, Oliver T; Keppler, Oliver T.

Cell Rep Med ; 5(4): 101483, 2024 Apr 16.

Artigo em Inglês | MEDLINE | ID: mdl-38579727

13.

A semi-automated method for isolating functionally intact mitochondria from cultured cells and tissue biopsies.

Schmitt, Sabine; Saathoff, Friederike; Meissner, Lilja; Schropp, Eva-Maria; Lichtmannegger, Josef; Schulz, Sabine; Eberhagen, Carola; Borchard, Sabine; Aichler, Michaela; Adamski, Jerzy; Plesnila, Nikolaus; Rothenfusser, Simon; Kroemer, Guido; Zischka, Hans.

Anal Biochem ; 443(1): 66-74, 2013 Dec 01.

Artigo em Inglês | MEDLINE | ID: mdl-23969012

14.

Major immunophenotypic abnormalities in patients with primary adrenal insufficiency of different etiology.

Nowotny, Hanna F; Marchant Seiter, Thomas; Ju, Jing; Gottschlich, Adrian; Schneider, Holger; Zopp, Stephanie; Vogel, Frederick; Tschaidse, Lea; Auer, Matthias K; Lottspeich, Christian; Kobold, Sebastian; Rothenfusser, Simon; Beuschlein, Felix; Reincke, Martin; Braun, Leah; Reisch, Nicole.

Front Immunol ; 14: 1275828, 2023.

Artigo em Inglês | MEDLINE | ID: mdl-38045693

15.

Bispecific antibodies redirect synthetic agonistic receptor modified T cells against melanoma.

Märkl, Florian; Benmebarek, Mohamed-Reda; Keyl, Julius; Cadilha, Bruno L; Geiger, Martina; Karches, Clara; Obeck, Hannah; Schwerdtfeger, Melanie; Michaelides, Stefanos; Briukhovetska, Daria; Stock, Sophia; Jobst, Jakob; Müller, Philipp Jie; Majed, Lina; Seifert, Matthias; Klüver, Anna-Kristina; Lorenzini, Theo; Grünmeier, Ruth; Thomas, Moritz; Gottschlich, Adrian; Klaus, Richard; Marr, Carsten; von Bergwelt-Baildon, Michael; Rothenfusser, Simon; Levesque, Mitchell P; Heppt, Markus Vincent; Endres, Stefan; Klein, Christian; Kobold, Sebastian.

J Immunother Cancer ; 11(5)2023 05.

Artigo em Inglês | MEDLINE | ID: mdl-37208128

16.

Reply.

Hoffmann, Franziska; Endres, Stefan; Rothenfusser, Simon.

Hepatology ; 63(3): 1062-3, 2016 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-26106015

17.

Immunostimulatory RNA blocks suppression by regulatory T cells.

Anz, David; Koelzer, Viktor H; Moder, Stefan; Thaler, Raffael; Schwerd, Tobias; Lahl, Katharina; Sparwasser, Tim; Besch, Robert; Poeck, Hendrik; Hornung, Veit; Hartmann, Gunther; Rothenfusser, Simon; Bourquin, Carole; Endres, Stefan.

J Immunol ; 184(2): 939-46, 2010 Jan 15.

Artigo em Inglês | MEDLINE | ID: mdl-19966212

18.

5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I.

Schmidt, Andreas; Schwerd, Tobias; Hamm, Wolfgang; Hellmuth, Johannes C; Cui, Sheng; Wenzel, Michael; Hoffmann, Franziska S; Michallet, Marie-Cecile; Besch, Robert; Hopfner, Karl-Peter; Endres, Stefan; Rothenfusser, Simon.

Proc Natl Acad Sci U S A ; 106(29): 12067-72, 2009 Jul 21.

Artigo em Inglês | MEDLINE | ID: mdl-19574455

19.

High-Throughput Platform for Detection of Neutralizing Antibodies Using Flavivirus Reporter Replicon Particles.

Lücke, Arlen-Celina; Vom Hemdt, Anja; Wieseler, Janett; Fischer, Carlo; Feldmann, Marie; Rothenfusser, Simon; Drexler, Jan Felix; Kümmerer, Beate Mareike.

Viruses ; 14(2)2022 02 08.

Artigo em Inglês | MEDLINE | ID: mdl-35215941

20.

FluoRNT: A robust, efficient assay for the detection of neutralising antibodies against yellow fever virus 17D.

Scheck, Magdalena K; Lehmann, Lisa; Zaucha, Magdalena; Schwarzlmueller, Paul; Huber, Kristina; Pritsch, Michael; Barba-Spaeth, Giovanna; Thorn-Seshold, Oliver; Krug, Anne B; Endres, Stefan; Rothenfusser, Simon; Thorn-Seshold, Julia.

PLoS One ; 17(2): e0262149, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-35139078

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